Bacillus coagulans has received much attention in animal husbandry in recent years. This feed additive raw material, with its unique effects, has brought many benefits to animal health, production performance, and breeding environment.

Bacillus coagulans, Gram positive, belongs to the phylum Firmicutes. Bacillus coagulans belongs to the genus Bacillus in taxonomy, with rod-shaped cells, Gram positive bacteria, terminal spores, and no flagella. It decomposes sugars to produce L-lactic acid, which is a homologous lactic acid fermentation bacterium. The optimal growth temperature is 45-50 ℃ and the optimal pH is 6.6-7.0.

In previous studies, a variety of effective antibacterial substances were isolated and purified from Bacillus amyloliquefaciens, and its application in pig industry is reviewed in order to provide reference for development of the application of Bacillus amyloliquefaciens as a safe and green probiotic.

In recent years, domestic and foreign research has found that the antibacterial mechanism of Bacillus amyloliquefaciens mainly includes the production of antagonistic and lytic effects.

​It has been confirmed that Bacillus amyloliquefaciens can produce polyketide compounds and explored its possible mechanism. Furthermore, Lipopeptide substances are one of the main antibacterial substances produced by Bacillus amyloliquefaciens.

The advantages of microbial agents in aquaculture are increasingly recognized. However, some conditionally pathogenic Bacillus species can cause diseases such as skin rot and sepsis in aquatic animals, and their safe use has become an issue that cannot be ignored in the aquaculture water environment.

Bacillus amyloliquefaciens is very common probiotic, which has been proven beneficial to the breeding industry. In recent years, the application in aquaculture has attracted widespread attention.

Microecological preparations, antimicrobial peptides, and feed enzyme preparations can be used as supplements and substitutes for antibiotics, and Bacillus amyloliquefaciens has these three functions, so it has attracted the attention of many researchers.

From the previous articles, it can be concluded that Bacillus amyloliquefaciens can improve the feed utilization efficiency of animals. This article delves into the mechanism of action of this bacteria.